SYNTHESIS AND TAUTOMERISM OF NEW 1-n-ALKYL-5-PYRAZOLONE DERIVATIVES
نویسندگان
چکیده
منابع مشابه
Isoquinoline Promoted Synthesis of alkyl 2-(1-alkyl-5-oxo-3-phenyl-2-thioxotetrahydro-4H-imidazol-4-yliden) acetate derivatives
Derivatives of thiazolidinone ring systems are known to act as anti-HIV infections , analgesic, anti-bacterial, anti-convulsant, anti parasitic, potential anti-inflammatory and herbicidal agents. Due biological activities of thiazolidinones ring, several methods for their synthesis have been illustrated in literature. Imidazolidine-2-thiones were synthesized by the oxidative cyclization of 1-be...
متن کاملSynthesis and Study of Analgesic, Anti-inflammatory Activities of 3-methyl-5- Pyrazolone Derivatives
Considerable amount of research has been carried out in the field of pyrazolone derivatives due to their diverse biological, pharmacological and chemical properties. The need was felt to synthesize certain 3-methyl-5-pyrazolone derivatives with potent analgesic and anti-inflammatory activity and with lesser side effects as it had been proved of late that the beneficial effects of pyrazolones ou...
متن کاملisoquinoline promoted synthesis of alkyl 2-(1-alkyl-5-oxo-3-phenyl-2-thioxotetrahydro-4h-imidazol-4-yliden) acetate derivatives
derivatives of thiazolidinone ring systems are known to act as anti-hiv infections , analgesic, anti-bacterial, anti-convulsant, anti parasitic, potential anti-inflammatory and herbicidal agents. due biological activities of thiazolidinones ring, several methods for their synthesis have been illustrated in literature. imidazolidine-2-thiones were synthesized by the oxidative cyclization of 1-be...
متن کاملNew N-alkyl derivatives of amphotericin B. Synthesis and biological properties.
Amphotericin B (AMB), Fig. 1 , the polyene macrolide antifungal antibiotic of high clinical importance, is the drug of choice for the treatment of deep-seated disseminated mycotic infections in humans1'2). However, the therapy is associated with toxic side effects, the most serious being the nephrotoxicity3). These undesirable effects are consequences of the poor selectivity of AMBinteraction w...
متن کاملSynthesis of pyrazolone derivatives and their biological activities
3-Methyl-1-phenylpyrazol-5-one and its derivatives prepared using ethyl acetoacetate, phenyl hydrazine and its derivatives. Ethyl acetoacetate reacted with phenylhydrazine at reflux temperature to give 3-methyl-1-phenylpyrazol-5-one crude and recrystlized from diluted ethanol to give pure 3-methyl1-phenylpyrazol-5-one. Different pyrazolone derivatives were prepared by using different phenyl hyd...
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ژورنال
عنوان ژورنال: Boletín de la Sociedad Chilena de Química
سال: 1999
ISSN: 0366-1644
DOI: 10.4067/s0366-16441999000300014